Caricamento...

Actinomycin D binds strongly to d(CGACGACG) and d(CGTCGTCG).

Earlier calorimetric studies had indicated that despite the absence of a GpC sequence, the self-complementary octamer d(CGTCGACG) binds strongly to actinomycin D (ACTD) with high cooperativity and a 2:1 drug/duplex ratio. A subsequent optical spectral study with related oligomers led us to suggest t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sha, F, Chen, F M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301099/
https://ncbi.nlm.nih.gov/pubmed/11023913
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !