Critical determinants of Ca(2+)-dependent inactivation within an EF-hand motif of L-type Ca(2+) channels.

L-type (alpha(1C)) calcium channels inactivate rapidly in response to localized elevation of intracellular Ca(2+), providing negative Ca(2+) feedback in a diverse array of biological contexts. The dominant Ca(2+) sensor for such Ca(2+)-dependent inactivation has recently been identified as calmoduli...

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Hlavní autoři: Peterson, B Z, Lee, J S, Mulle, J G, Wang, Y, de Leon, M, Yue, D T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300784/
https://ncbi.nlm.nih.gov/pubmed/10733970
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