Local movement in the S2 region of the voltage-gated potassium channel hKv2.1 studied using cysteine mutagenesis.

The positively charged S4 region of voltage-dependent potassium channels moves outward during depolarization, leading to channel opening, but possible movement of the negatively charged S2 region may be more complex. Here we have studied possible movement of the S2 region of the slowly activating hu...

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Main Authors: Milligan, C J, Wray, D
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300779/
https://ncbi.nlm.nih.gov/pubmed/10733965
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