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In vitro correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

BACKGROUND: SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To evaluate potential of this technique for gene therapy it...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Principais autores: Sangiuolo, Federica, Bruscia, Emanuela, Serafino, Annalucia, Nardone, Anna Maria, Bonifazi, Emanuela, Lais, Monica, Gruenert, Dieter C, Novelli, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12243649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2350-3-8
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