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In vitro correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

BACKGROUND: SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To evaluate potential of this technique for gene therapy it...

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Udgivet i:BMC Med Genet
Principais autores: Sangiuolo, Federica, Bruscia, Emanuela, Serafino, Annalucia, Nardone, Anna Maria, Bonifazi, Emanuela, Lais, Monica, Gruenert, Dieter C, Novelli, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2002
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Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12243649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2350-3-8
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