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Atomic force microscopy imaging of DNA covalently immobilized on a functionalized mica substrate.

A procedure for covalent binding of DNA to a functionalized mica substrate is described. The approach is based on photochemical cross-linking of DNA to immobilized psoralen derivatives. A tetrafluorphenyl (TFP) ester of trimethyl psoralen (trioxalen) was synthesized, and the procedure to immobilize...

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Detalhes bibliográficos
Main Authors: Shlyakhtenko, L S, Gall, A A, Weimer, J J, Hawn, D D, Lyubchenko, Y L
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300353/
https://ncbi.nlm.nih.gov/pubmed/10388781
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