Loss of conformational stability in calmodulin upon methionine oxidation.

We have used electrospray ionization mass spectrometry (ESI-MS), circular dichroism (CD), and fluorescence spectroscopy to investigate the secondary and tertiary structural consequences that result from oxidative modification of methionine residues in wheat germ calmodulin (CaM), and prevent activat...

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Autors principals: Gao, J, Yin, D H, Yao, Y, Sun, H, Qin, Z, Schöneich, C, Williams, T D, Squier, T C
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299464/
https://ncbi.nlm.nih.gov/pubmed/9512014
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