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An Altered Mode of Calcium Coordination in Methionine-Oxidized Calmodulin
Oxidation of methionine residues in calmodulin (CaM) lowers the affinity for calcium and results in an inability to activate target proteins fully. To evaluate the structural consequences of CaM oxidation, we used infrared difference spectroscopy to identify oxidation-dependent effects on protein co...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Biophysical Society
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586565/ https://ncbi.nlm.nih.gov/pubmed/18723592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.139634 |
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