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Conditional gene knock-down by CRE-dependent short interfering RNAs
Short interfering RNAs (siRNAs) are short (21–23 nt) double-stranded RNAs that direct the sequence-specific degradation of corresponding mRNAs, resulting in suppression of gene activity. siRNAs are powerful tools for gene functional analysis in mammals. Chemically synthesized siRNAs permit transient...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1298975/ https://ncbi.nlm.nih.gov/pubmed/14726950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400064 |
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