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Methodological obstacles in knocking down small noncoding RNAs

In the recent past, several thousand noncoding RNA (ncRNA) genes have been predicted within eukaryal genomes. However, for their functional analysis only a few high-throughput methods are currently available to knock down selected ncRNA species, such as microRNAs, which are targeted by antisense pro...

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Detalhes bibliográficos
Main Authors: Ploner, Andreas, Ploner, Christian, Lukasser, Melanie, Niederegger, Harald, Hüttenhofer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743047/
https://ncbi.nlm.nih.gov/pubmed/19690100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1740009
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