A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens

Eukaryotic cells constantly have to fight against internal acidification. In mammals, this task is mainly performed by the ubiquitously expressed electroneutral Na(+)/H(+) exchanger NHE-1, which activates in a cooperative manner when cells become acidic. Despite its biological importance, the mechan...

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Hlavní autoři: Lacroix, Jérôme, Poët, Mallorie, Maehrel, Céline, Counillon, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
Scientific Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298952/
https://ncbi.nlm.nih.gov/pubmed/14710192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400035
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