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A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens
Eukaryotic cells constantly have to fight against internal acidification. In mammals, this task is mainly performed by the ubiquitously expressed electroneutral Na(+)/H(+) exchanger NHE-1, which activates in a cooperative manner when cells become acidic. Despite its biological importance, the mechan...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1298952/ https://ncbi.nlm.nih.gov/pubmed/14710192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400035 |
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