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EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice

BACKGROUND: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer. With the available treatments, survival does not exceed 12–14 mo from the time of diagnosis. We describe a novel strategy to selectively induce the death of glioblastoma cells and other cancer cells that over-express...

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Bibliografiske detaljer
Main Authors: Shir, Alexei, Ogris, Manfred, Wagner, Ernst, Levitzki, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298941/
https://ncbi.nlm.nih.gov/pubmed/16318410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030006
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