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EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice.
BACKGROUND: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer. With the available treatments, survival does not exceed 12-14 mo from the time of diagnosis. We describe a novel strategy to selectively induce the death of glioblastoma cells and other cancer cells that over-express...
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| Formato: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2005-12-01
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| Colecção: | PLoS Medicine |
| Acesso em linha: | http://dx.doi.org/10.1371/journal.pmed.0030006 |
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