Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau

The R406W tau mutation found in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) causes a hereditary tauopathy clinically resembling Alzheimer's disease. Expression of modest levels of the longest human tau isoform with this mutation under the control of the α-calcium–calmo...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Tatebayashi, Yoshitaka, Miyasaka, Tomohiro, Chui, De-Hua, Akagi, Takumi, Mishima, Ken-ichi, Iwasaki, Katsunori, Fujiwara, Michihiro, Tanemura, Kentaro, Murayama, Miyuki, Ishiguro, Koichi, Planel, Emmanuel, Sato, Shinji, Hashikawa, Tsutomu, Takashima, Akihiko
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 2002
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.202205599
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