Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau

The R406W tau mutation found in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) causes a hereditary tauopathy clinically resembling Alzheimer's disease. Expression of modest levels of the longest human tau isoform with this mutation under the control of the α-calcium–...

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Bibliografiska uppgifter
Huvudupphovsmän: Tatebayashi, Yoshitaka, Miyasaka, Tomohiro, Chui, De-Hua, Akagi, Takumi, Mishima, Ken-ichi, Iwasaki, Katsunori, Fujiwara, Michihiro, Tanemura, Kentaro, Murayama, Miyuki, Ishiguro, Koichi, Planel, Emmanuel, Sato, Shinji, Hashikawa, Tsutomu, Takashima, Akihiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2002
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC129794/
https://ncbi.nlm.nih.gov/pubmed/12368474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202205599
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