טוען...
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR)
The nuclear receptor PXR (pregnane X receptor) protects the body from hepatotoxicity of secondary bile acids such as lithocholic acid (LCA) by inducing expression of the hydroxylating cytochrome P450 enzyme CYP3A and promoting detoxification. We found that activation of PXR also increases the activi...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The National Academy of Sciences
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129778/ https://ncbi.nlm.nih.gov/pubmed/12370413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212494599 |
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