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Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-K(b) molecules

Crosslinking of the T cell receptor has been proposed to be a prerequisite for T cell activation. Although the evidence supports this notion for CD4 T cells, the situation for CD8 T cells is less clear. Soluble class I monomers have been used to determine activation requirements in vitro with contra...

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Autores principales: Schott, Eckart, Bertho, Nicolas, Ge, Qing, Maurice, Madelon M., Ploegh, Hidde L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC129760/
https://ncbi.nlm.nih.gov/pubmed/12374858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212515399
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