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Soluble peptide–MHC monomers cause activation of CD8(+) T cells through transfer of the peptide to T cell MHC molecules
T cell receptor (TCR)-mediated activation of CD4(+) T cells is known to require multivalent engagement of the TCR by, for example, oligomeric peptide–MHC complexes. In contrast, for CD8(+) T cells, there is evidence for TCR-mediated activation by univalent engagement of the TCR. We have here compare...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129758/ https://ncbi.nlm.nih.gov/pubmed/12374859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212515299 |
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