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Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase

Antibodies specific for glucose-6-phosphate isomerase (G6PI) from T-cell receptor transgenic K/BxN mice are known to induce arthritis in mice, and immunization of DBA/1 mice with G6PI led to acute arthritis without permanent deformation of their joints. Because rheumatoid arthritis is a chronic dise...

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Autores principales: Bockermann, Robert, Schubert, David, Kamradt, Thomas, Holmdahl, Rikard
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297579/
https://ncbi.nlm.nih.gov/pubmed/16277685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1829
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