The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression

The 3′ Ig heavy chain locus (Igh) regulatory region is the most downstream known element of the murine Igh gene cluster. We report here that the nearest non-Igh genes—Crip, Crp2, and Mta1—are located ≈70 kb further downstream and are beyond the end of the domain of Igh transcriptional regulation. We...

Description complète

Détails bibliographiques

Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Zhou, Jie, Ashouian, Nasrin, Delepine, Marc, Matsuda, Fumihiko, Chevillard, Christophe, Riblet, Roy, Schildkraut, Carl L., Birshtein, Barbara K.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2002
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212392399
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!