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The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression
The 3′ Ig heavy chain locus (Igh) regulatory region is the most downstream known element of the murine Igh gene cluster. We report here that the nearest non-Igh genes—Crip, Crp2, and Mta1—are located ≈70 kb further downstream and are beyond the end of the domain of Igh transcriptional regulation. We...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129745/ https://ncbi.nlm.nih.gov/pubmed/12370427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212392399 |
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