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Structure and function of the platelet integrin α(IIb)β(3)

The platelet integrin α(IIb)β(3) is required for platelet aggregation. Like other integrins, α(IIb)β(3) resides on cell surfaces in an equilibrium between inactive and active conformations. Recent experiments suggest that the shift between these conformations involves a global reorganization of the...

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Bibliographic Details
Main Author: Bennett, Joel S.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297263/
https://ncbi.nlm.nih.gov/pubmed/16322781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26989
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