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A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19
Adeno-associated virus (AAV) undergoes site-specific integration into human chromosome 19 through a deletion-substitution mechanism at the well characterized AAVS1 site. We have shown previously that a cis element within the left end of the AAV genome enhances the efficiency of Rep-mediated site-spe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129453/ https://ncbi.nlm.nih.gov/pubmed/12221283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182430299 |
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