Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function

Divalent metal transporter 1 (DMT1) mediates apical iron uptake into duodenal enterocytes and also transfers iron from the endosome into the cytosol after cellular uptake via the transferrin receptor. Hence, mutations in DMT1 cause systemic iron deficiency and anemia. DMT1 mRNA levels are increased...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hubert, Nadia, Hentze, Matthias W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12209011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192423399
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