Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function

Divalent metal transporter 1 (DMT1) mediates apical iron uptake into duodenal enterocytes and also transfers iron from the endosome into the cytosol after cellular uptake via the transferrin receptor. Hence, mutations in DMT1 cause systemic iron deficiency and anemia. DMT1 mRNA levels are increased...

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Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Hubert, Nadia, Hentze, Matthias W.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2002
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12209011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192423399
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