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Alternative splicing generates isoform diversity in MEN1

Although the gene MEN1 has a long-standing association with cancer, its mechanisms of action remain incompletely understood, acting both as a tumour suppressor in neuroendocrine tumours and as an oncogene in leukaemia. The best-characterised isoform of the encoded protein, MENIN, is the 610-amino ac...

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Principais autores: Anassuya Ramachandran, Polona Le Quesne Stabej, Veronica Boyle, Marianne S Elston, Sharon Pattison, Ben Lawrence, Cris Print
Format: Artigo
Sprog:Inglês
Udgivet: Bioscientifica 2024-11-01
Serier:Endocrine Oncology
Fag:
men1
menin
isoforms
alternative splicing
mutation
Online adgang:https://eo.bioscientifica.com/view/journals/eo/4/1/EO-24-0014.xml
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