Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment accessibility

Antigen receptor gene assembly is regulated by transcriptional promoters and enhancers, which control the accessibility of gene segments to a lymphocyte-specific V(D)J recombinase. However, it remained unclear whether accessibility depends on the process of transcription itself or chromatin modifica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sikes, Michael L., Meade, Amber, Tripathi, Rajkamal, Krangel, Michael S., Oltz, Eugene M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2002
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC129441/
https://ncbi.nlm.nih.gov/pubmed/12196630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182166699
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