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Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment accessibility
Antigen receptor gene assembly is regulated by transcriptional promoters and enhancers, which control the accessibility of gene segments to a lymphocyte-specific V(D)J recombinase. However, it remained unclear whether accessibility depends on the process of transcription itself or chromatin modifica...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129441/ https://ncbi.nlm.nih.gov/pubmed/12196630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182166699 |
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