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Tumor necrosis factor-α regulation of CD4(+)C25(+) T cell levels in NOD mice
The mechanism by which tumor necrosis factor-α (TNF) differentially modulates type I diabetes mellitus in the nonobese diabetic (NOD) mouse is not well understood. CD4(+)CD25(+) T cells have been implicated as mediators of self-tolerance. We show (i) NOD mice have a relative deficiency of CD4(+)CD25...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129437/ https://ncbi.nlm.nih.gov/pubmed/12221281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172382999 |
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