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Tumor necrosis factor-α regulation of CD4(+)C25(+) T cell levels in NOD mice

The mechanism by which tumor necrosis factor-α (TNF) differentially modulates type I diabetes mellitus in the nonobese diabetic (NOD) mouse is not well understood. CD4(+)CD25(+) T cells have been implicated as mediators of self-tolerance. We show (i) NOD mice have a relative deficiency of CD4(+)CD25...

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Bibliografische gegevens
Hoofdauteurs: Wu, Ava J., Hua, Hong, Munson, Sibyl H., McDevitt, Hugh O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC129437/
https://ncbi.nlm.nih.gov/pubmed/12221281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172382999
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