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A Critical Role for Lymphotoxin-β Receptor in the Development of Diabetes in Nonobese Diabetic Mice

To assess the role of lymphotoxin-β receptor (LTβR) in diabetes pathogenesis, we expressed an LTβR–Fc fusion protein in nonobese diabetic (NOD) mice. The fusion protein was expressed in the embryo, reached high levels for the first 2 wk after birth, and then declined progressively with age. High exp...

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Detalhes bibliográficos
Main Authors: Ettinger, Rachel, Munson, Sibyl H., Chao, Cheng-Chi, Vadeboncoeur, Mary, Toma, Jon, McDevitt, Hugh O.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193386/
https://ncbi.nlm.nih.gov/pubmed/11390441
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