Dual localization of human DNA topoisomerase IIIα to mitochondria and nucleus

The human TOP3α gene encoding DNA topoisomerase IIIα (hTop3α) has two potential start codons for the synthesis of proteins 1,001 and 976 aa residues in length. The sequence of the N-terminal region of the 1,001-residue form resembles signal peptide sequences for mitochondrial import, and fluorescenc...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Wang, Yong, Lyu, Yi Lisa, Wang, James C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12209014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192449499
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