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Inhibition of hypochlorous acid-induced cellular toxicity by nitrite

Chronic inflammation results in increased nitrogen monoxide (⋅NO) formation and the accumulation of nitrite (NO [Formula: see text]). Neutrophils stimulated by various inflammatory mediators release myeloperoxidase to produce the cytotoxic agent hypochlorous acid (HOCl). Exposure of chondrocytic SW1...

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Autors principals: Whiteman, Matthew, Hooper, D. Craig, Scott, Gwen S., Koprowski, Hilary, Halliwell, Barry
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC129398/
https://ncbi.nlm.nih.gov/pubmed/12221280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152462399
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