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Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
Optimal activation of T cells requires effective occupancy of both the antigen-specific T cell receptor and a second coreceptor such as CD28. We used cDNA microarrays to characterize the genomic expression program in human peripheral T cells responding to stimulation of these receptors. We found tha...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129348/ https://ncbi.nlm.nih.gov/pubmed/12195013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092284399 |
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