Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors

Signals generated by T cell receptor (TCR) and CD28 engagement are required for optimal T cell activation, but how these signals integrate within the cell is still largely unknown. We have used near genome-scale expression profiling to monitor T cell signal transduction pathways triggered via TCR an...

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Autors principals: Riley, James L., Mao, Mao, Kobayashi, Sumire, Biery, Matt, Burchard, Julja, Cavet, Guy, Gregson, Brian P., June, Carl H., Linsley, Peter S.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC129347/
https://ncbi.nlm.nih.gov/pubmed/12195015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162359999
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