Evidence for an ancient selective sweep in the MHC class I gene repertoire of chimpanzees

MHC class I molecules play an essential role in the immune defense against intracellular infections. The hallmark of the MHC is its extensive degree of polymorphism at the population level. However, the present comparison of MHC class I gene intron variation revealed that chimpanzees have experience...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: de Groot, Natasja G., Otting, Nel, Doxiadis, Gaby G. M., Balla-Jhagjhoorsingh, Sunita S., Heeney, Jonathan L., van Rood, Jon J., Gagneux, Pascal, Bontrop, Ronald E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2002
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC129340/
https://ncbi.nlm.nih.gov/pubmed/12186979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182420799
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