Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

Structural genomics is emerging as a principal approach to define protein structure–function relationships. To apply this approach on a genomic scale, novel methods and technologies must be developed to determine large numbers of structures. We describe the design and implementation of a high-throug...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Lesley, Scott A., Kuhn, Peter, Godzik, Adam, Deacon, Ashley M., Mathews, Irimpan, Kreusch, Andreas, Spraggon, Glen, Klock, Heath E., McMullan, Daniel, Shin, Tanya, Vincent, Juli, Robb, Alyssa, Brinen, Linda S., Miller, Mitchell D., McPhillips, Timothy M., Miller, Mark A., Scheibe, Daniel, Canaves, Jaume M., Guda, Chittibabu, Jaroszewski, Lukasz, Selby, Thomas L., Elsliger, Marc-Andre, Wooley, John, Taylor, Susan S., Hodgson, Keith O., Wilson, Ian A., Schultz, Peter G., Stevens, Raymond C.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2002
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12193646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142413399
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