Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

Structural genomics is emerging as a principal approach to define protein structure–function relationships. To apply this approach on a genomic scale, novel methods and technologies must be developed to determine large numbers of structures. We describe the design and implementation of a high-throug...

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Autori principali: Lesley, Scott A., Kuhn, Peter, Godzik, Adam, Deacon, Ashley M., Mathews, Irimpan, Kreusch, Andreas, Spraggon, Glen, Klock, Heath E., McMullan, Daniel, Shin, Tanya, Vincent, Juli, Robb, Alyssa, Brinen, Linda S., Miller, Mitchell D., McPhillips, Timothy M., Miller, Mark A., Scheibe, Daniel, Canaves, Jaume M., Guda, Chittibabu, Jaroszewski, Lukasz, Selby, Thomas L., Elsliger, Marc-Andre, Wooley, John, Taylor, Susan S., Hodgson, Keith O., Wilson, Ian A., Schultz, Peter G., Stevens, Raymond C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC129326/
https://ncbi.nlm.nih.gov/pubmed/12193646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142413399
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