Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

Structural genomics is emerging as a principal approach to define protein structure–function relationships. To apply this approach on a genomic scale, novel methods and technologies must be developed to determine large numbers of structures. We describe the design and implementation of a high-throug...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lesley, Scott A., Kuhn, Peter, Godzik, Adam, Deacon, Ashley M., Mathews, Irimpan, Kreusch, Andreas, Spraggon, Glen, Klock, Heath E., McMullan, Daniel, Shin, Tanya, Vincent, Juli, Robb, Alyssa, Brinen, Linda S., Miller, Mitchell D., McPhillips, Timothy M., Miller, Mark A., Scheibe, Daniel, Canaves, Jaume M., Guda, Chittibabu, Jaroszewski, Lukasz, Selby, Thomas L., Elsliger, Marc-Andre, Wooley, John, Taylor, Susan S., Hodgson, Keith O., Wilson, Ian A., Schultz, Peter G., Stevens, Raymond C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12193646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142413399
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