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Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

Promoters are molecular ‘modules’, which are controlled as individual entities yet are often analyzed by nuclease digestion methodologies which, a priori, destroy this modularity. About 40% of mammalian genes contain CpG islands in their promoters and exonic regions, which are normally unmethylated....

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Bibliografski detalji
Glavni autori: Fatemi, Mehrnaz, Pao, Martha M., Jeong, Shinwu, Gal-Yam, Einav Nili, Egger, Gerda, Weisenberger, Daniel J., Jones, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1292996/
https://ncbi.nlm.nih.gov/pubmed/16314307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni180
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