Reversal of experimental colitis disease activity in mice following administration of an adenoviral IL-10 vector

Genetic deficiency in the expression of interleukin-10 (IL-10) is associated with the onset and progression of experimental inflammatory bowel disease (IBD). The clinical significance of IL-10 expression is supported by studies showing that immune-augmentation of IL-10 prevents inflammation and muco...

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Autori principali: Sasaki, Makoto, Mathis, J Michael, Jennings, Merilyn H, Jordan, Paul, Wang, Yuping, Ando, Tomoaki, Joh, Takashi, Alexander, J Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291390/
https://ncbi.nlm.nih.gov/pubmed/16259632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-2-13
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