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Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/β-catenin signaling

BACKGROUND: Secreted Frizzled related proteins (SFRPs) are extracellular regulators of Wnt signaling. These proteins contain an N-terminal cysteine rich domain (CRD) highly similar to the CRDs of the Frizzled family of seven-transmembrane proteins that act as Wnt receptors. SFRPs can bind to Wnts an...

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Detalhes bibliográficos
Main Authors: Swain, Rajeeb Kumar, Katoh, Masaru, Medina, Araceli, Steinbeisser, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291380/
https://ncbi.nlm.nih.gov/pubmed/16236168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-3-12
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