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A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling

BACKGROUND: Activation of the Wnt signalling cascade is primarily based on the interplay between Wnt ligands, their receptors and extracellular modulators. One prominent family of extracellular modulators is represented by the SFRP (secreted Frizzled-related protein) family. These proteins have sign...

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Bibliographische Detailangaben
Hauptverfasser: Gorny, Anne-Kathrin, Kaufmann, Lilian T, Swain, Rajeeb K, Steinbeisser, Herbert
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077065/
https://ncbi.nlm.nih.gov/pubmed/24252524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-89
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