The iStem, a Long-Range RNA Secondary Structure Element Required for Efficient Exon Inclusion in the Drosophila Dscam Pre-mRNA

The Drosophila Dscam gene encodes 38,016 different proteins, due to alternative splicing of 95 of its 115 exons, that function in axon guidance and innate immunity. The alternative exons are organized into four clusters, and the exons within each cluster are spliced in a mutually exclusive manner. H...

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Bibliographic Details
Main Authors: Kreahling, Jenny M., Graveley, Brenton R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291239/
https://ncbi.nlm.nih.gov/pubmed/16287842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10251-10260.2005
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