Regulation of Dscam exon 17 alternative splicing by steric hindrance in combination with RNA secondary structures

The gene Down syndrome cell adhesion molecule (Dscam) potentially encodes 38 016 distinct isoforms in Drosophila melanogaster via mutually exclusive splicing. Here we reveal a combinatorial mechanism of regulation of Dscam exon 17 mutually exclusive splicing through steric hindrance in combination w...

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Bibliographic Details
Main Authors: Yue, Yuan, Li, Guoli, Yang, Yun, Zhang, Wenjing, Pan, Huawei, Chen, Ran, Shi, Feng, Jin, Yongfeng
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917985/
https://ncbi.nlm.nih.gov/pubmed/24448213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.27176
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