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Regulation of Dscam exon 17 alternative splicing by steric hindrance in combination with RNA secondary structures

The gene Down syndrome cell adhesion molecule (Dscam) potentially encodes 38 016 distinct isoforms in Drosophila melanogaster via mutually exclusive splicing. Here we reveal a combinatorial mechanism of regulation of Dscam exon 17 mutually exclusive splicing through steric hindrance in combination w...

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Detalhes bibliográficos
Main Authors: Yue, Yuan, Li, Guoli, Yang, Yun, Zhang, Wenjing, Pan, Huawei, Chen, Ran, Shi, Feng, Jin, Yongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917985/
https://ncbi.nlm.nih.gov/pubmed/24448213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.27176
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