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Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters

The class II transactivator (CIITA) is the master regulator of major histocompatibility complex class II (MHCII) transcription. Its activity is regulated at the post-transcriptional level by phosphorylation and oligomerization. This aggregation mapped to and depended on the phosphorylation of residu...

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Publicat a:EMBO J
Autors principals: Tosi, Giovanna, Jabrane-Ferrat, Nabila, Peterlin, B.Matija
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf557
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