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Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters

The class II transactivator (CIITA) is the master regulator of major histocompatibility complex class II (MHCII) transcription. Its activity is regulated at the post-transcriptional level by phosphorylation and oligomerization. This aggregation mapped to and depended on the phosphorylation of residu...

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Detalhes bibliográficos
Main Authors: Tosi, Giovanna, Jabrane-Ferrat, Nabila, Peterlin, B.Matija
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129089/
https://ncbi.nlm.nih.gov/pubmed/12374747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf557
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