Dimeric RFX Proteins Contribute to the Activity and Lineage Specificity of the Interleukin-5 Receptor α Promoter through Activation and Repression Domains

Interleukin-5 (IL-5) plays a central role in the differentiation, proliferation, and functional activation of eosinophils. The specific action of IL-5 on eosinophils and hematopoietically related basophils is regulated by the restricted expression of IL-5 receptor α (IL-5Rα), a subunit of high-affin...

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Main Authors: Iwama, Atsushi, Pan, Jing, Zhang, Pu, Reith, Walter, Mach, Bernard, Tenen, Daniel G., Sun, Zijie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104353/
https://ncbi.nlm.nih.gov/pubmed/10330134
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