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Expression of the Three Human Major Histocompatibility Complex Class II Isotypes Exhibits a Differential Dependence on the Transcription Factor RFXAP

Major histocompatibility complex class II (MHCII) molecules play a pivotal role in the immune system because they direct the development and activation of CD4(+) T cells. There are three human MHCII isotypes, HLA-DR, HLA-DQ, and HLA-DP. Key transcription factors controlling MHCII genes have been ide...

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Detalhes bibliográficos
Main Authors: Peretti, Marie, Villard, Jean, Barras, Emmanuèle, Zufferey, Madeleine, Reith, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87290/
https://ncbi.nlm.nih.gov/pubmed/11486010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5699-5709.2001
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