Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo

Caspases play a critical role in the execution of metazoan apoptosis and are thus attractive therapeutic targets for apoptosis-associated diseases. Here we report that baculovirus P49, a homolog of pancaspase inhibitor P35, prevents apoptosis in invertebrates by inhibiting an initiator caspase that...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Zoog, Stephen J., Schiller, Jennifer J., Wetter, Justin A., Chejanovsky, Nor, Friesen, Paul D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129042/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf520
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